Management of Chemotherapy-induced Nausea and Vomiting

Management of CINV

There are a number of factors to consider in the management of patients with CINV.

Prevention of CINV is the stated goal of all CINV treatment regimens.¹

Effective CINV prophylaxis offers the most effective treatment strategy.²

There are also a number of specific factors that may limit the ability to protect against CINV:

Gender³

Younger women (<50 years) are known to be more susceptible to CINV (e.g. those with breast and gynaecological cancer).

Oral mucositis and swallowing difficulties⁴

Oral mucositis is a common complication of chemotherapy and/or radiotherapy. This side effect causes significant morbidity and may delay the treatment plan, as well as require additional therapeutic intervention. It can lead to difficulty in swallowing, speaking and in taking oral medications.

Gastrointestinal absorption⁵

Oral antiemetic treatments require a functional gastrointestinal system.