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RECTOGESIC
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RECTOGESIC®

TOLERABILITY

RECTOGESIC 4 mg/g Rectal Ointment is indicated in adults for relief of pain associated with chronic anal fissure.

Click here for prescribing information and adverse event reporting.

Tolerability

RECTOGESIC has relieved the pain of over 3 million chronic anal fissures worldwide since launch.1 In a clinical trial consisting of 123 patients, over 86% of patients using RECTOGESIC completed their course of treatment with less than 6% discontinuing the study due to headache.2

In the same study, the most common adverse event was headache which occurred with an incidence of 69.9% in the RECTOGESIC group and 47.6% in the placebo group.3 Headache can be treated with simple analgesics such as paracetamol and is reversible on discontinuation of treatment.3

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  • References

    1. Kyowa Kirin Data on File - DOF-UK-073-Rectogesic.

    2. Berry SM, Barish CF, Bhandari R, et al. Nitroglycerin 0.4% ointment vs placebo in the treatment of pain resulting from chronic anal ssure: a randomized, double-blind, placebo-controlled study. BMC Gastroenterol. 2013 Jul 1;13:106.

    3. RECTOGESIC® (glyceryl trinitrate) Summary of Product Characteristics

    M-RCG-UK-11-23-0004 March 2024