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RECTOGESIC
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RECTOGESIC®

GLOSSARY

RECTOGESIC 4 mg/g Rectal Ointment is indicated in adults for relief of pain associated with chronic anal fissure.

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Glossary

Acute anal fissure – present for less than 6 weeks, superficial and with well-demarcated edges.

Anorectal – relating to, or involving both the anus and rectum.

Chronic fissures – tends to persist for 6 weeks or more, and is wider and deeper than acute anal fissures.

Fissure – a break or slit in tissue usually at the junction of skin and mucous membrane.

Glyceryl trinitrate (also known as nitroglycerin) – acts by dilating the arteries, increasing blood flow and improving blood supply to the heart. Glyceryl trinitrate ointment is the main ingredient in RECTOGESIC 4mg/g and alleviates the pain of anal fissure by relaxing the muscles of the anal sphincter, reducing anal pressure, and improving blood flow to the site of the fissure.1

Nitric oxide – acts as a vasodilator (blood vessel relaxant), it controls blood flow to tissues.2

Topical anaesthetics – used to numb the skin and reduce pain.3

Average:

  • References

    1. Fenton C et al. Drugs. 2006;66:343-9.

    2. Medicine Net, nitric oxide definition. Available at: https://www.medicinenet.com/what_does_nitric_oxide_do_to_your_body/article.htm Last accessed: March 2024.

    3. NHS Treatment Advice. Anal fissure. Available at: https://www.nhs.uk/conditions/anal-fissure/treatment Last accessed: March 2024.

    M-RCG-UK-11-23-0004 March 2024